There are two types of assays available:
- SensiScreen® Ready-to-use CE-IVD Assays: SensiScreen® Ready-to-use assays are pre-dispensed in PCR strips and require only addition of patient DNA for somatic mutation testing.
- SensiScreen® Dispense Ready CE-IVD Mixes: SensiScreen® Dispense Ready CE-IVD Mixes include all reagents for somatic mutation testing except plastic ware to be used with the real-time PCR system of choice.
Overview of mutations detected by SensiScreen®
SensiScreen® assays detect the most common somatic mutations present in KRAS, NRAS, BRAF and EGFR. Furthermore, a range of new assays is expected to be added to the portfolio in 2017.
BRAF mutations detected by SensiScreen®
|Assay||CDS mutation||Amino acid mutation||Cosmic ID|
|BRAF exon 15||c.1799_1800TG>AT||Val600Asp (V600D)||COSM477|