Microsatellites or Short Tandem Repeats (STRs) are DNA sequences with short repetitive units of 1-6 bases, present throughout the whole genome. At the same locus, microsatellites are of different length in different individuals due to different number of repeats.
The detection of microsatellites length variability is a very powerful tool used in research, quality control, forensics and diagnostics to determine genealogy between different individuals or to identify different species.
By using AL high resolutions Spreadex® gels after PCR amplification of microsatellite markers, even small differences in length can be distinguished. The chemically inert non-acrylamide matrix allows downstream reactions like re-amplification (PCR), sequencing or cloning, without previous purification.
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